PAIP1 Antikörper

Produktnummer ABIN7117636

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PAIP1 in WB, ELISA und IF. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte und Affe.

Kurzübersicht für PAIP1 Antikörper (ABIN7117636)

Target: PAIP1 (Poly(A) Binding Protein Interacting Protein 1 (PAIP1))

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-PAIP1 Antikörper

Verwendungszweck: PAIP1 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: poly(A) binding protein interacting protein 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IF: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu PAIP1

Target: PAIP1 (Poly(A) Binding Protein Interacting Protein 1 (PAIP1))

Andere Bezeichnung: PAIP1

Hintergrund:

Synonyms: Polyadenylate-binding protein-interacting protein 1 (PABP-interacting protein 1, PAIP-1, Poly(A)-binding protein-interacting protein 1)|PAIP1

Background: Acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability(mCRD) domain.

Molekulargewicht: 60 kDa, 51 kDa, 40 kDa

Gen-ID: 10605

UniProt: Q9H074